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Efficacy and Safety of Guselkumab in Japanese Patients With Palmoplantar Pustulosis: A Phase 3 Randomized Clinical Trial

IMPORTANCE: Palmoplantar pustulosis (PPP) causes erythematous, scaly plaques with recurrent sterile pustules refractory to treatment and with few randomized clinical trials conducted. Evidence points to involvement of interleukin 23 in the pathogenesis of PPP. OBJECTIVE: To determine the efficacy an...

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Detalles Bibliográficos
Autores principales: Terui, Tadashi, Kobayashi, Satomi, Okubo, Yukari, Murakami, Masamoto, Zheng, Richuan, Morishima, Hitomi, Goto, Ryosuke, Kimura, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613288/
https://www.ncbi.nlm.nih.gov/pubmed/31268476
http://dx.doi.org/10.1001/jamadermatol.2019.1394