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Nerve Growth Factor Pathobiology During the Progression of Alzheimer’s Disease

The current review summarizes the pathobiology of nerve growth factor (NGF) and its cognate receptors during the progression of Alzheimer’s disease (AD). Both transcript and protein data indicate that cholinotrophic neuronal dysfunction is related to an imbalance between TrkA-mediated survival signa...

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Detalles Bibliográficos
Autores principales: Mufson, Elliott J., Counts, Scott E., Ginsberg, Stephen D., Mahady, Laura, Perez, Sylvia E., Massa, Stephen M., Longo, Frank M., Ikonomovic, Milos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613497/
https://www.ncbi.nlm.nih.gov/pubmed/31312116
http://dx.doi.org/10.3389/fnins.2019.00533