Mutant p53 increases exosome-mediated transfer of miR-21-3p and miR-769-3p to promote pulmonary metastasis

OBJECTIVE: Tumor metastasis is a complex, multistep process that depends on tumor cells and their communication with the tumor microenvironment. A p53 gain-of-function mutant has been shown to enhance the tumorigenesis, invasion, and metastasis abilities of tumor cells. This study aimed to investiga...

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Detalles Bibliográficos
Autores principales: Ju, Qiang, Zhao, Lina, Gao, Jiajia, Zhou, Lanping, Xu, Yang, Sun, Yulin, Zhao, Xiaohang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613506/
https://www.ncbi.nlm.nih.gov/pubmed/31354222
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.03.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613506/
https://www.ncbi.nlm.nih.gov/pubmed/31354222
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.03.15

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