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Therapeutic Targeting of Notch Signaling Pathway in Hematological Malignancies
The Notch pathway plays a key role in several processes, including stem-cell self-renewal, proliferation, and cell differentiation. Several studies identified recurrent mutations in hematological malignancies making Notch one of the most desirable targets in leukemia and lymphoma. The Notch signalin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Università Cattolica del Sacro Cuore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613627/ https://www.ncbi.nlm.nih.gov/pubmed/31308913 http://dx.doi.org/10.4084/MJHID.2019.037 |