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Therapeutic Targeting of Notch Signaling Pathway in Hematological Malignancies

The Notch pathway plays a key role in several processes, including stem-cell self-renewal, proliferation, and cell differentiation. Several studies identified recurrent mutations in hematological malignancies making Notch one of the most desirable targets in leukemia and lymphoma. The Notch signalin...

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Detalles Bibliográficos
Autores principales:	Sorrentino, Claudia, Cuneo, Antonio, Roti, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Università Cattolica del Sacro Cuore 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613627/ https://www.ncbi.nlm.nih.gov/pubmed/31308913 http://dx.doi.org/10.4084/MJHID.2019.037

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