T vector velocity: A new ECG biomarker for identifying drug effects on cardiac ventricular repolarization

BACKGROUND: We present a new family of ECG biomarkers for assessing drug effects on ventricular repolarization. We show that drugs blocking inward (depolarizing) ion currents cause a relative increase of the T vector velocity (TVV) and accelerate repolarization, while drugs blocking outward ion curr...

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Detalles Bibliográficos
Autores principales: Bystricky, Werner, Maier, Christoph, Gintant, Gary, Bergau, Dennis, Kamradt, Kent, Welsh, Patrick, Carter, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613676/
https://www.ncbi.nlm.nih.gov/pubmed/31283756
http://dx.doi.org/10.1371/journal.pone.0204712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613676/
https://www.ncbi.nlm.nih.gov/pubmed/31283756
http://dx.doi.org/10.1371/journal.pone.0204712

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