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ICOS deficiency hampers the homeostasis, development and function of NK cells

Signaling through the inducible costimulator ICOS is required for the homeostasis and function of various immune cell populations, with an outstanding role in the generation and maintenance of germinal centers. Very recently, it has been suggested that the clinical phenotype of ICOS-deficient patien...

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Detalles Bibliográficos
Autores principales: Montes-Casado, María, Ojeda, Gloria, Aragoneses-Fenoll, Laura, López, Daniel, de Andrés, Belén, Gaspar, María Luisa, Dianzani, Umberto, Rojo, José M., Portolés, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613708/
https://www.ncbi.nlm.nih.gov/pubmed/31283790
http://dx.doi.org/10.1371/journal.pone.0219449