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Arterivirus nsp4 Antagonizes Interferon Beta Production by Proteolytically Cleaving NEMO at Multiple Sites

Equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) represent two members of the family Arteriviridae and pose major threats for the horse- and swine-breeding industries worldwide. A previous study suggested that PRRSV nsp4, a 3C-like protease, antagonizes in...

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Detalles Bibliográficos
Autores principales: Chen, Jiyao, Wang, Dang, Sun, Zheng, Gao, Li, Zhu, Xinyu, Guo, Jiahui, Xu, Shangen, Fang, Liurong, Li, Kui, Xiao, Shaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613749/
https://www.ncbi.nlm.nih.gov/pubmed/30944180
http://dx.doi.org/10.1128/JVI.00385-19