Unbiased screen of RNA tailing activities reveals a poly(UG) polymerase

Ribonucleotidyl transferases (rNTases) add non-templated ribonucleotides to diverse RNAs. We developed TRAID-Seq, a screening strategy in S. cerevisiae to identify sequences added to a reporter RNA at single-nucleotide resolution by overexpressing candidate enzymes from different organisms. The rNTa...

Descripción completa

Detalles Bibliográficos
Autores principales: Preston, Melanie A., Porter, Douglas F., Chen, Fan, Buter, Natascha, Lapointe, Christopher P., Keles, Sunduz, Kimble, Judith, Wickens, Marvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613791/
https://www.ncbi.nlm.nih.gov/pubmed/30988468
http://dx.doi.org/10.1038/s41592-019-0370-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613791/
https://www.ncbi.nlm.nih.gov/pubmed/30988468
http://dx.doi.org/10.1038/s41592-019-0370-6

Ejemplares similares