Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T Cell Therapy for Solid Tumors

While impressive clinical responses have been observed using chimeric antigen receptor (CAR) T cells targeting CD19+ hematologic malignancies, limited clinical benefit has been observed using CAR T cells for a variety of solid tumors. Results of clinical studies have highlighted several obstacles wh...

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Detalles Bibliográficos
Autores principales: Mata, Melinda, Gottschalk, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613829/
https://www.ncbi.nlm.nih.gov/pubmed/30796733
http://dx.doi.org/10.1007/s40265-019-01071-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613829/
https://www.ncbi.nlm.nih.gov/pubmed/30796733
http://dx.doi.org/10.1007/s40265-019-01071-7

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