Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth

UVRAG (UV radiation resistance associated) is an important regulator of mammalian macroautophagy/autophagy by interacting with BECN1, PIK3C3, and RUBCN. Phosphorylation of UVRAG by MTORC1 negatively regulates autophagosome maturation under nutrient-enriched conditions. However, how UVRAG ubiquitinat...

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Detalles Bibliográficos
Autores principales: Feng, Xing, Jia, Yanyan, Zhang, Yuyu, Ma, Fei, Zhu, Yuekun, Hong, Xuehui, Zhou, Qingxin, He, Ruixing, Zhang, Heng, Jin, Junfei, Piao, Daxun, Huang, He, Li, Qinghua, Qiu, Xingfeng, Zhang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper - Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613838/
https://www.ncbi.nlm.nih.gov/pubmed/30686098
http://dx.doi.org/10.1080/15548627.2019.1570063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613838/
https://www.ncbi.nlm.nih.gov/pubmed/30686098
http://dx.doi.org/10.1080/15548627.2019.1570063

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