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Efficient HIV-1 Trans Infection of CD4(+) T Cells Occurs in the Presence of Antiretroviral Therapy

BACKGROUND: Antiretroviral therapy (ART) has dramatically improved the quality of life of people with HIV-1 infection (PWH). However, it is not curative, and interruption of ART results in rapid viral rebound. Cell-to-cell transfer of HIV-1, or trans infection, is a highly efficient mechanism of vir...

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Detalles Bibliográficos
Autores principales: Rappocciolo, Giovanna, Sluis-Cremer, Nicolas, Rinaldo, Charles R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613953/
https://www.ncbi.nlm.nih.gov/pubmed/31304185
http://dx.doi.org/10.1093/ofid/ofz253