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The First Generation of iPSC Line from a Korean Alzheimer's Disease Patient Carrying APP-V715M Mutation Exhibits a Distinct Mitochondrial Dysfunction

Alzheimer's Disease (AD) is a progressive neurodegenerative disease, which is pathologically defined by the accumulation of amyloid plaques and hyper-phosphorylated tau aggregates in the brain. Mitochondrial dysfunction is also a prominent feature in AD, and the extracellular Aβ and phosphoryla...

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Detalles Bibliográficos
Autores principales: Li, Ling, Roh, Jee Hoon, Kim, Hee Jin, Park, Hyun Jung, Kim, Minchul, Koh, Wonyoung, Heo, Hyohoon, Chang, Jong Wook, Nakanishi, Mahito, Yoon, Taeyoung, Na, Duk L., Song, Jihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614069/
https://www.ncbi.nlm.nih.gov/pubmed/31308793
http://dx.doi.org/10.5607/en.2019.28.3.329