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Gait Ignition Failure in JNPL3 Human Tau-mutant Mice

Cognitive impairments and motor dysfunction are commonly observed behavioral phenotypes in genetic animal models of neurodegenerative diseases. JNPL3 transgenic mice expressing human P301L-mutant tau display motor disturbances with age- and gene dose-dependent development of neurofibrillary tangles,...

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Detalles Bibliográficos
Autores principales: Jang, HoChung, Ryu, Jung Hwa, Shin, Kyung Min, Seo, Na-young, Kim, Gyu Hyun, Huh, Yang Hoon, Pae, Ae Nim, Lee, Kea Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614071/
https://www.ncbi.nlm.nih.gov/pubmed/31308799
http://dx.doi.org/10.5607/en.2019.28.3.404