Putative role of conserved water molecules in the hydration and inter-domain recognition of mono nuclear copper centers in O2-bound human ceruloplasmin: A comparative study between X-ray and MD simulated structures

Human Ceruloplasmin (hCP) is an unique multicopper oxidase which involves in different biological functions e.g., iron metabolism, copper transportation, biogenic amine oxidation ,and its malfunction causes Wilson's and Menkes diseases. MD- simulation studies of O2- bound solvated structure hav...

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Detalles Bibliográficos
Autor principal: Mukhopadhyay, Bishnu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614124/
https://www.ncbi.nlm.nih.gov/pubmed/31312077
http://dx.doi.org/10.6026/97320630015402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614124/
https://www.ncbi.nlm.nih.gov/pubmed/31312077
http://dx.doi.org/10.6026/97320630015402

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