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Putative role of conserved water molecules in the hydration and inter-domain recognition of mono nuclear copper centers in O2-bound human ceruloplasmin: A comparative study between X-ray and MD simulated structures
Human Ceruloplasmin (hCP) is an unique multicopper oxidase which involves in different biological functions e.g., iron metabolism, copper transportation, biogenic amine oxidation ,and its malfunction causes Wilson's and Menkes diseases. MD- simulation studies of O2- bound solvated structure hav...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Biomedical Informatics
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614124/ https://www.ncbi.nlm.nih.gov/pubmed/31312077 http://dx.doi.org/10.6026/97320630015402 |