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Hypertrophy of human embryonic stem cell–derived cardiomyocytes supported by positive feedback between Ca(2+) and diacylglycerol signals
Human embryonic stem cell–derived cardiomyocytes develop pronounced hypertrophy in response to angiotensin-2, endothelin-1, and a selected mix of three fatty acids. All three of these responses are accompanied by increases in both basal cytoplasmic Ca(2+) and diacylglycerol, quantified with the Ca(2...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614165/ https://www.ncbi.nlm.nih.gov/pubmed/31250095 http://dx.doi.org/10.1007/s00424-019-02293-0 |