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Hypertrophy of human embryonic stem cell–derived cardiomyocytes supported by positive feedback between Ca(2+) and diacylglycerol signals

Human embryonic stem cell–derived cardiomyocytes develop pronounced hypertrophy in response to angiotensin-2, endothelin-1, and a selected mix of three fatty acids. All three of these responses are accompanied by increases in both basal cytoplasmic Ca(2+) and diacylglycerol, quantified with the Ca(2...

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Detalles Bibliográficos
Autores principales: Deisl, Christine, Fine, Michael, Moe, Orson W., Hilgemann, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614165/
https://www.ncbi.nlm.nih.gov/pubmed/31250095
http://dx.doi.org/10.1007/s00424-019-02293-0

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