Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

Cancer cells with heterogeneous mutation landscapes and extensive functional redundancy easily develop resistance to monotherapies by emerging activation of compensating or bypassing pathways. To achieve more effective and sustained clinical responses, synergistic interactions of multiple druggable...

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Detalles Bibliográficos
Autores principales: Tang, Jing, Gautam, Prson, Gupta, Abhishekh, He, Liye, Timonen, Sanna, Akimov, Yevhen, Wang, Wenyu, Szwajda, Agnieszka, Jaiswal, Alok, Turei, Denes, Yadav, Bhagwan, Kankainen, Matti, Saarela, Jani, Saez-Rodriguez, Julio, Wennerberg, Krister, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614366/
https://www.ncbi.nlm.nih.gov/pubmed/31312514
http://dx.doi.org/10.1038/s41540-019-0098-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614366/
https://www.ncbi.nlm.nih.gov/pubmed/31312514
http://dx.doi.org/10.1038/s41540-019-0098-z

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