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Differences in placental capillary shear stress in fetal growth restriction may affect endothelial cell function and vascular network formation

Fetal growth restriction (FGR) affects 5–10% of pregnancies, leading to clinically significant fetal morbidity and mortality. FGR placentae frequently exhibit poor vascular branching, but the mechanisms driving this are poorly understood. We hypothesize that vascular structural malformation at the o...

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Detalles Bibliográficos
Autores principales: Tun, Win M., Yap, Choon Hwai, Saw, Shier Nee, James, Joanna L., Clark, Alys R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614400/
https://www.ncbi.nlm.nih.gov/pubmed/31285454
http://dx.doi.org/10.1038/s41598-019-46151-6