The effect of X-linked dosage compensation on complex trait variation

Quantitative genetics theory predicts that X-chromosome dosage compensation (DC) will have a detectable effect on the amount of genetic and therefore phenotypic trait variances at associated loci in males and females. Here, we systematically examine the role of DC in humans in 20 complex traits in a...

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Detalles Bibliográficos
Autores principales: Sidorenko, Julia, Kassam, Irfahan, Kemper, Kathryn E., Zeng, Jian, Lloyd-Jones, Luke R., Montgomery, Grant W., Gibson, Greg, Metspalu, Andres, Esko, Tonu, Yang, Jian, McRae, Allan F., Visscher, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614401/
https://www.ncbi.nlm.nih.gov/pubmed/31285442
http://dx.doi.org/10.1038/s41467-019-10598-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614401/
https://www.ncbi.nlm.nih.gov/pubmed/31285442
http://dx.doi.org/10.1038/s41467-019-10598-y

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