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Drp1 and RB interaction to mediate mitochondria-dependent necroptosis induced by cadmium in hepatocytes

Mitochondrial quality control (MQC) is implicated in cell death induced by heavy metal pollutants. Dynamin-related protein 1 (Drp1) regulates mitochondrial fission, which is an important part of MQC. Retinoblastoma (RB) protein can regulate MQC in a transcription-independent manner. Necroptosis play...

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Detalles Bibliográficos
Autores principales: Zhang, Shili, Che, Lin, He, Chengyong, Huang, Jing, Guo, Nijun, Shi, Jiazhang, Lin, Yuchun, Lin, Zhongning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614419/
https://www.ncbi.nlm.nih.gov/pubmed/31285421
http://dx.doi.org/10.1038/s41419-019-1730-y