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Drp1 and RB interaction to mediate mitochondria-dependent necroptosis induced by cadmium in hepatocytes
Mitochondrial quality control (MQC) is implicated in cell death induced by heavy metal pollutants. Dynamin-related protein 1 (Drp1) regulates mitochondrial fission, which is an important part of MQC. Retinoblastoma (RB) protein can regulate MQC in a transcription-independent manner. Necroptosis play...
Autores principales: | Zhang, Shili, Che, Lin, He, Chengyong, Huang, Jing, Guo, Nijun, Shi, Jiazhang, Lin, Yuchun, Lin, Zhongning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614419/ https://www.ncbi.nlm.nih.gov/pubmed/31285421 http://dx.doi.org/10.1038/s41419-019-1730-y |
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