Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death

The new type 2 diabetes drug, dapagliflozin, reduces blood glucose levels and body weight by inhibiting sodium glucose transporter 2 (SGLT2) in proximal tubular cells. SGLT2 inhibitors might modulate glucose influx into renal tubular cells, thereby regulating the metabolic conditions that cause endo...

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Detalles Bibliográficos
Autores principales: Shibusawa, Ryo, Yamada, Eijiro, Okada, Shuichi, Nakajima, Yasuyo, Bastie, Claire C., Maeshima, Akito, Kaira, Kyoichi, Yamada, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614429/
https://www.ncbi.nlm.nih.gov/pubmed/31285506
http://dx.doi.org/10.1038/s41598-019-46402-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614429/
https://www.ncbi.nlm.nih.gov/pubmed/31285506
http://dx.doi.org/10.1038/s41598-019-46402-6

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