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Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death

The new type 2 diabetes drug, dapagliflozin, reduces blood glucose levels and body weight by inhibiting sodium glucose transporter 2 (SGLT2) in proximal tubular cells. SGLT2 inhibitors might modulate glucose influx into renal tubular cells, thereby regulating the metabolic conditions that cause endo...

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Detalles Bibliográficos
Autores principales:	Shibusawa, Ryo, Yamada, Eijiro, Okada, Shuichi, Nakajima, Yasuyo, Bastie, Claire C., Maeshima, Akito, Kaira, Kyoichi, Yamada, Masanobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614429/ https://www.ncbi.nlm.nih.gov/pubmed/31285506 http://dx.doi.org/10.1038/s41598-019-46402-6

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