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Distribution of fitness effects of mutations obtained from a simple genetic regulatory network model

Beneficial and deleterious mutations change an organism’s fitness but the distribution of these mutational effects on fitness are unknown. Several experimental, theoretical, and computational studies have explored this question but are limited because of experimental restrictions, or disconnect with...

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Detalles Bibliográficos
Autores principales: Brajesh, R. G., Dutta, Dibyendu, Saini, Supreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614479/
https://www.ncbi.nlm.nih.gov/pubmed/31285500
http://dx.doi.org/10.1038/s41598-019-46401-7