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Distribution of fitness effects of mutations obtained from a simple genetic regulatory network model
Beneficial and deleterious mutations change an organism’s fitness but the distribution of these mutational effects on fitness are unknown. Several experimental, theoretical, and computational studies have explored this question but are limited because of experimental restrictions, or disconnect with...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614479/ https://www.ncbi.nlm.nih.gov/pubmed/31285500 http://dx.doi.org/10.1038/s41598-019-46401-7 |