CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-κB activation

The Keap1-Nrf2-ARE pathway regulates the constitutive and inducible transcription of various genes that encode detoxification enzymes, antioxidant proteins and anti-inflammatory proteins and has pivotal roles in the defence against cellular oxidative stress. In this study, we investigated the therap...

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Detalles Bibliográficos
Autores principales: Lu, Meng-Chen, Zhao, Jing, Liu, Yu-Ting, Liu, Tian, Tao, Meng-Min, You, Qi-Dong, Jiang, Zheng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614503/
https://www.ncbi.nlm.nih.gov/pubmed/31279986
http://dx.doi.org/10.1016/j.redox.2019.101266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614503/
https://www.ncbi.nlm.nih.gov/pubmed/31279986
http://dx.doi.org/10.1016/j.redox.2019.101266

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