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Copper ion / H(2)O(2) oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
Copper ion-catalyzed oxidation of yeast SOD1 (ySOD1) was examined to determine early oxidative modifications, including oxidation of a crucial disulfide bond, and the structural and functional repercussions of these events. The study used distinct oxidative conditions: Cu(2+)/H(2)O(2), Cu(2+)/H(2)O(...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614508/ https://www.ncbi.nlm.nih.gov/pubmed/31284117 http://dx.doi.org/10.1016/j.redox.2019.101262 |