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Elevated HOX gene expression in acute myeloid leukemia is associated with NPM1 mutations and poor survival
Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cells and the most common malignant myeloid disorder in adults. Several gene mutations such as in NPM1 (nucleophosmin 1) are involved in the pathogenesis and progression of AML. The aim of this study was to identify genes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614546/ https://www.ncbi.nlm.nih.gov/pubmed/31333881 http://dx.doi.org/10.1016/j.jare.2019.05.006 |