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Elevated HOX gene expression in acute myeloid leukemia is associated with NPM1 mutations and poor survival

Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cells and the most common malignant myeloid disorder in adults. Several gene mutations such as in NPM1 (nucleophosmin 1) are involved in the pathogenesis and progression of AML. The aim of this study was to identify genes...

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Detalles Bibliográficos
Autores principales: Nagy, Ádám, Ősz, Ágnes, Budczies, Jan, Krizsán, Szilvia, Szombath, Gergely, Demeter, Judit, Bödör, Csaba, Győrffy, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614546/
https://www.ncbi.nlm.nih.gov/pubmed/31333881
http://dx.doi.org/10.1016/j.jare.2019.05.006

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