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Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
A large number of natural products have been advocated as anticancer agents. Many of these compounds contain functional groups characterized by chemical reactivity. It is not clear whether distinct mechanisms of action can be attributed to such compounds. We used a chemical library screening approac...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614553/ https://www.ncbi.nlm.nih.gov/pubmed/31285509 http://dx.doi.org/10.1038/s41598-019-46168-x |