Total Synthesis of an Immunogenic Trehalose Phospholipid from Salmonella Typhi and Elucidation of Its sn-Regiochemistry by Mass Spectrometry

[Image: see text] Diphosphatidyltrehalose (diPT) is an immunogenic glycolipid, recently isolated from Salmonella Typhi. Despite rigorous structure elucidation, the sn-position of the acyl chains on the glycerol backbone had not been unequivocally established. A stereoselective synthesis of diPT and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mishra, Vivek K., Buter, Jeffrey, Blevins, Molly S., Witte, Martin D., Van Rhijn, Ildiko, Moody, D. Branch, Brodbelt, Jennifer S., Minnaard, Adriaan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614791/
https://www.ncbi.nlm.nih.gov/pubmed/31247773
http://dx.doi.org/10.1021/acs.orglett.9b01725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614791/
https://www.ncbi.nlm.nih.gov/pubmed/31247773
http://dx.doi.org/10.1021/acs.orglett.9b01725

Ejemplares similares