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In vitro isolation of class-specific oligonucleotide-based small-molecule receptors

Class-specific bioreceptors are highly desirable for recognizing structurally similar small molecules, but the generation of such affinity elements has proven challenging. We here develop a novel ‘parallel-and-serial’ selection strategy for isolating class-specific oligonucleotide-based receptors (a...

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Detalles Bibliográficos
Autores principales: Yang, Weijuan, Yu, Haixiang, Alkhamis, Obtin, Liu, Yingzhu, Canoura, Juan, Fu, Fengfu, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614805/
https://www.ncbi.nlm.nih.gov/pubmed/30926988
http://dx.doi.org/10.1093/nar/gkz224