Nonsense mutation-dependent reinitiation of translation in mammalian cells

In-frame stop codons mark the termination of translation. However, post-termination ribosomes can reinitiate translation at downstream AUG codons. In mammals, reinitiation is most efficient when the termination codon is positioned close to the 5′-proximal initiation site and around 78 bases upstream...

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Detalles Bibliográficos
Autores principales: Cohen, Sarit, Kramarski, Lior, Levi, Shahar, Deshe, Noa, Ben David, Oshrit, Arbely, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614817/
https://www.ncbi.nlm.nih.gov/pubmed/31045216
http://dx.doi.org/10.1093/nar/gkz319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614817/
https://www.ncbi.nlm.nih.gov/pubmed/31045216
http://dx.doi.org/10.1093/nar/gkz319

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