Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics

The viral RNA (vRNA) genome of influenza viruses is replicated by the RNA-dependent RNA polymerase (RNAP) via a complementary RNA (cRNA) intermediate. The vRNA promoter can adopt multiple conformations when bound by the RNAP. However, the dynamics, determinants, and biological role of these conforma...

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Detalles Bibliográficos
Autores principales: Robb, Nicole C, te Velthuis, Aartjan J W, Fodor, Ervin, Kapanidis, Achillefs N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614853/
https://www.ncbi.nlm.nih.gov/pubmed/31032520
http://dx.doi.org/10.1093/nar/gkz313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614853/
https://www.ncbi.nlm.nih.gov/pubmed/31032520
http://dx.doi.org/10.1093/nar/gkz313

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