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Joint Estimates of Heterozygosity and Runs of Homozygosity for Modern and Ancient Samples

Both the total amount and the distribution of heterozygous sites within individual genomes are informative about the genetic diversity of the population they belong to. Detecting true heterozygous sites in ancient genomes is complicated by the generally limited coverage achieved and the presence of...

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Detalles Bibliográficos
Autores principales: Renaud, Gabriel, Hanghøj, Kristian, Korneliussen, Thorfinn Sand, Willerslev, Eske, Orlando, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614887/
https://www.ncbi.nlm.nih.gov/pubmed/31088861
http://dx.doi.org/10.1534/genetics.119.302057