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Three Decades of Amyloid Beta Synthesis: Challenges and Advances

Aggregation of the pathological amyloid beta (Aβ) isoform Aβ(1−42) into senile plaques is a neuropathological hallmark of Alzheimer's disease (AD). The biochemical significance of this phenomenon therefore necessitates the need for ready access to Aβ(1−42) for research purposes. Chemical synthe...

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Detalles Bibliográficos
Autores principales: Kasim, Johanes K., Kavianinia, Iman, Harris, Paul W. R., Brimble, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614915/
https://www.ncbi.nlm.nih.gov/pubmed/31334219
http://dx.doi.org/10.3389/fchem.2019.00472