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Dietary Glycotoxins Impair Hepatic Lipidemic Profile in Diet-Induced Obese Rats Causing Hepatic Oxidative Stress and Insulin Resistance

Nonalcoholic fatty liver disease (NAFLD) is caused by excessive liver lipid accumulation, but insulin resistance is specifically associated with impaired lipid saturation, oxidation, and storage (esterification), besides increased de novo lipogenesis. We hypothesized that dietary glycotoxins could i...

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Detalles Bibliográficos
Autores principales: Neves, C., Rodrigues, T., Sereno, J., Simões, C., Castelhano, J., Gonçalves, J., Bento, G., Gonçalves, S., Seiça, R., Domingues, M. R., Castelo-Branco, M., Matafome, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614994/
https://www.ncbi.nlm.nih.gov/pubmed/31341532
http://dx.doi.org/10.1155/2019/6362910