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Elaboration and characterization of curcumin-loaded Tri-CL-mPEG three-arm copolymeric nanoparticles by a microchannel technology

Purpose: Clinical applications of curcumin (Cur) have been greatly restricted due to its low solubility and poor systemic bioavailability. Three-arm amphiphilic copolymer tricarballylic acid-poly (ε-caprolactone)-methoxypolyethylene glycol (Tri-CL-mPEG) nanoparticles (NPs) were designed to improve t...

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Detalles Bibliográficos
Autores principales: Wu, Wenchao, Wu, Jiangqing, Fu, Qiafan, Jin, Chenhao, Guo, Fangyuan, Yan, Qinying, Yang, Qingliang, Wu, Danjun, Yang, Yan, Yang, Gensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615023/
https://www.ncbi.nlm.nih.gov/pubmed/31308653
http://dx.doi.org/10.2147/IJN.S198217