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Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells

BACKGROUND: In the era of personalized therapy, functional annotation of less frequent genetic aberrations will be instrumental in adapting effective therapeutic in clinic. Overexpression of Melanoma associated antigen A3 (MAGEA3) is reported in certain pancreatic cancer (PCA) patients. The major ob...

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Detalles Bibliográficos
Autores principales: Das, Biswajit, Senapati, Shantibhusan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615156/
https://www.ncbi.nlm.nih.gov/pubmed/31287009
http://dx.doi.org/10.1186/s13046-019-1272-2