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STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes

BACKGROUND: Leukostasis is a key patho-physiological event responsible for capillary occlusion in diabetic retinopathy. Circulating monocytes are the main cell type entrapped in retinal vessels in diabetes. In this study, we investigated the role of the signal transducer and activator of transcripti...

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Detalles Bibliográficos
Autores principales: Chen, Mei, Obasanmi, Gideon, Armstrong, David, Lavery, Nuala-Jane, Kissenpfennig, Adrien, Lois, Noemi, Xu, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615157/
https://www.ncbi.nlm.nih.gov/pubmed/31286987
http://dx.doi.org/10.1186/s12974-019-1533-1