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STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes
BACKGROUND: Leukostasis is a key patho-physiological event responsible for capillary occlusion in diabetic retinopathy. Circulating monocytes are the main cell type entrapped in retinal vessels in diabetes. In this study, we investigated the role of the signal transducer and activator of transcripti...
Autores principales: | Chen, Mei, Obasanmi, Gideon, Armstrong, David, Lavery, Nuala-Jane, Kissenpfennig, Adrien, Lois, Noemi, Xu, Heping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615157/ https://www.ncbi.nlm.nih.gov/pubmed/31286987 http://dx.doi.org/10.1186/s12974-019-1533-1 |
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