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Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE(2) pathway

BACKGROUND: Triggering receptor expressed on myeloid cells-1 (TREM-1) is inducible on monocyte/macrophages and neutrophils and amplifies the inflammatory response. The aim of this study was to determine whether rheumatoid arthritis synovial fibroblasts (RASF) promote the expression of TREM-1 in mono...

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Detalles Bibliográficos
Autores principales: Peng, Anping, Lu, Xinyi, Huang, Jun, He, Min, Xu, Jianhua, Huang, Hui, Chen, Qubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615166/
https://www.ncbi.nlm.nih.gov/pubmed/31287012
http://dx.doi.org/10.1186/s13075-019-1954-3