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Regulation of CD137 expression through K-Ras signaling in pancreatic cancer cells
BACKGROUND: The interaction between CD137 and its ligand (CD137L) plays a major role in the regulation of immune functions and affects cancer immunotherapy. CD137 is a cell surface protein mainly located on activated T cells, and its regulation and functions in immune cells are well established. How...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615207/ https://www.ncbi.nlm.nih.gov/pubmed/31288851 http://dx.doi.org/10.1186/s40880-019-0386-4 |