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Regulation of CD137 expression through K-Ras signaling in pancreatic cancer cells

BACKGROUND: The interaction between CD137 and its ligand (CD137L) plays a major role in the regulation of immune functions and affects cancer immunotherapy. CD137 is a cell surface protein mainly located on activated T cells, and its regulation and functions in immune cells are well established. How...

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Detalles Bibliográficos
Autores principales: Glorieux, Christophe, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615207/
https://www.ncbi.nlm.nih.gov/pubmed/31288851
http://dx.doi.org/10.1186/s40880-019-0386-4