DLGAP1 directs megakaryocytic growth and differentiation in an MPL dependent manner in hematopoietic cells

BACKGROUND: The MPL protein is a major regulator of megakaryopoiesis and platelet formation as well as stem cell regulation. Aberrant MPL and downstream Jak/STAT signaling results in the development of the Myeloproliferative Neoplasms (MPN). The pathogenetic and phenotypic features of the classical...

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Detalles Bibliográficos
Autores principales: Kwiatkowski, Boguslaw A., Burwick, Nicolas R., Richard, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615210/
https://www.ncbi.nlm.nih.gov/pubmed/31321035
http://dx.doi.org/10.1186/s40364-019-0165-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615210/
https://www.ncbi.nlm.nih.gov/pubmed/31321035
http://dx.doi.org/10.1186/s40364-019-0165-z

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