Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an oncogene, which upregulates in approximately 70% of human cancers. Autophagy is an evolutionarily conserved process which maintains cellular homeostasis and eliminates damaged cellular components. Moreover, the STAT3 signal...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shichong, Yang, Lehe, Yao, Yulei, Xu, Lingyuan, Xiang, Youqun, Zhao, Haiyang, Wang, Liangxing, Zuo, Zhigui, Huang, Xiaoying, Zhao, Chengguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615228/
https://www.ncbi.nlm.nih.gov/pubmed/31287013
http://dx.doi.org/10.1186/s13046-019-1303-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615228/
https://www.ncbi.nlm.nih.gov/pubmed/31287013
http://dx.doi.org/10.1186/s13046-019-1303-z

Ejemplares similares