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Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy
BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an oncogene, which upregulates in approximately 70% of human cancers. Autophagy is an evolutionarily conserved process which maintains cellular homeostasis and eliminates damaged cellular components. Moreover, the STAT3 signal...
Autores principales: | Lin, Shichong, Yang, Lehe, Yao, Yulei, Xu, Lingyuan, Xiang, Youqun, Zhao, Haiyang, Wang, Liangxing, Zuo, Zhigui, Huang, Xiaoying, Zhao, Chengguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615228/ https://www.ncbi.nlm.nih.gov/pubmed/31287013 http://dx.doi.org/10.1186/s13046-019-1303-z |
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