Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness

BACKGROUND: Bladder cancer progression has been associated with dysfunctional repair of double-strand breaks (DSB), a deleterious type of DNA lesions that fuel genomic instability. Accurate DSB repair relies on two distinct pathways, homologous recombination (HR) and classical non-homologous end-joi...

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Detalles Bibliográficos
Autores principales: Richter, Christin, Marquardt, Stephan, Li, Fanghua, Spitschak, Alf, Murr, Nico, Edelhäuser, Berdien A. H., Iliakis, George, Pützer, Brigitte M., Logotheti, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615232/
https://www.ncbi.nlm.nih.gov/pubmed/31287003
http://dx.doi.org/10.1186/s13046-019-1286-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615232/
https://www.ncbi.nlm.nih.gov/pubmed/31287003
http://dx.doi.org/10.1186/s13046-019-1286-9

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