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Effect of food intake on respiratory chemosensitivity to CO(2) in young adults

BACKGROUND: Food intake augments CO(2) production; however, minute ventilation is not augmented during exercise after food intake. Respiratory chemoreceptors respond to CO(2) and influence respiration. We examined the effect of food intake on respiratory chemosensitivity to CO(2) in young adults. ME...

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Autores principales: Hayashi, Keiji, Suekuni, Misato, Sugiyama, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615250/
https://www.ncbi.nlm.nih.gov/pubmed/31287028
http://dx.doi.org/10.1186/s40101-019-0200-7
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author Hayashi, Keiji
Suekuni, Misato
Sugiyama, Koji
author_facet Hayashi, Keiji
Suekuni, Misato
Sugiyama, Koji
author_sort Hayashi, Keiji
collection PubMed
description BACKGROUND: Food intake augments CO(2) production; however, minute ventilation is not augmented during exercise after food intake. Respiratory chemoreceptors respond to CO(2) and influence respiration. We examined the effect of food intake on respiratory chemosensitivity to CO(2) in young adults. METHODS: The hypercapnic ventilatory response was measured in eleven healthy individuals before and after food intake. To evaluate the respiratory chemoreflex response to CO(2), minute ventilation was plotted against end-tidal PCO(2) using data obtained with the rebreathing method. RESULTS: Sublingual temperature, CO(2) output, minute ventilation, and end-tidal PCO(2) were all significantly higher at baseline in the session after food intake than in the session before food intake. On the other hand, there was no significant difference in chemosensitivity to CO(2) between the sessions before and after food intake (1.60 ± 0.62 vs. 1.53 ± 0.62 l min(−1) mmHg(−1)). CONCLUSIONS: Food intake does not influence respiratory chemosensitivity to CO(2) in young adults, which is different from infants. This suggests that control of respiration differs between young adults and infants and that the elevated minute ventilation after food intake in young adults is not caused by a change in respiratory chemosensitivity.
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spelling pubmed-66152502019-07-18 Effect of food intake on respiratory chemosensitivity to CO(2) in young adults Hayashi, Keiji Suekuni, Misato Sugiyama, Koji J Physiol Anthropol Short Report BACKGROUND: Food intake augments CO(2) production; however, minute ventilation is not augmented during exercise after food intake. Respiratory chemoreceptors respond to CO(2) and influence respiration. We examined the effect of food intake on respiratory chemosensitivity to CO(2) in young adults. METHODS: The hypercapnic ventilatory response was measured in eleven healthy individuals before and after food intake. To evaluate the respiratory chemoreflex response to CO(2), minute ventilation was plotted against end-tidal PCO(2) using data obtained with the rebreathing method. RESULTS: Sublingual temperature, CO(2) output, minute ventilation, and end-tidal PCO(2) were all significantly higher at baseline in the session after food intake than in the session before food intake. On the other hand, there was no significant difference in chemosensitivity to CO(2) between the sessions before and after food intake (1.60 ± 0.62 vs. 1.53 ± 0.62 l min(−1) mmHg(−1)). CONCLUSIONS: Food intake does not influence respiratory chemosensitivity to CO(2) in young adults, which is different from infants. This suggests that control of respiration differs between young adults and infants and that the elevated minute ventilation after food intake in young adults is not caused by a change in respiratory chemosensitivity. BioMed Central 2019-07-08 /pmc/articles/PMC6615250/ /pubmed/31287028 http://dx.doi.org/10.1186/s40101-019-0200-7 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Hayashi, Keiji
Suekuni, Misato
Sugiyama, Koji
Effect of food intake on respiratory chemosensitivity to CO(2) in young adults
title Effect of food intake on respiratory chemosensitivity to CO(2) in young adults
title_full Effect of food intake on respiratory chemosensitivity to CO(2) in young adults
title_fullStr Effect of food intake on respiratory chemosensitivity to CO(2) in young adults
title_full_unstemmed Effect of food intake on respiratory chemosensitivity to CO(2) in young adults
title_short Effect of food intake on respiratory chemosensitivity to CO(2) in young adults
title_sort effect of food intake on respiratory chemosensitivity to co(2) in young adults
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615250/
https://www.ncbi.nlm.nih.gov/pubmed/31287028
http://dx.doi.org/10.1186/s40101-019-0200-7
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